Sentence examples for measured protein binding from inspiring English sources

Exact(2)

The CDN measured protein binding was 86.9%.

It has been suggested that glutathione reduces the measured protein binding, possibly acting as an alternative partner in the formation of a disulphide.

Similar(58)

Differential solubilization to measure protein binding to cytoskeletal proteins demonstrated that p-Tau in the A53T mutant mouse were unbound to cytoskeletal proteins, consistent with dissociation of p-Tau from the microtubules upon hyperphosphorylation. Interestingly, α-Syn remained tightly bound to the cytoskeleton, while p-GSK-3β was seen in the cytoskeleton-free fractions.

Higher amounts of laminin were detected on the surface of GPTMS posts (Imean = 32.7 ± 7.6 au) than on APTESglut posts (Imean = 23.2 ± 4.2 au; Figure 2C), suggesting the existence of higher protein surface density on GPTMS treated microposts We used fluorescently conjugated gelatin to measure protein binding to organosilanes as an alternative to ICC staining and as a control of observed results.

One common technique for measuring protein-binding affinities uses flow cytometry to analyze ligand binding to proteins presented on the surface of a cell.

It can be seen from Table 4 that the postprocessing application increases significantly the correlation coefficient between calculated and experimentally measured protein-ligand binding energies and decreases appreciably number of false positives predictions.

This is reflected by a >15-fold shift in MCL-1 affinity in the presence of 10% human serum and measured human protein binding >99%.

With the difficulty in measuring brain protein binding accurately when the free fraction is quite small, the high variability in measuring Tg2576 brain Aβ42 in vivo and the fact that there were no significant data points for brain Aβ42 lowering, we needed another study investigating free brain versus free plasma concentrations as the cause of Aβ42 reduction in the central compartment.

Furthermore, reported label-free measurements of small molecule interaction kinetics either are in low-throughput, nonmicroarray format or indirectly measure the protein binding signal instead of the small molecules.

Plasma 25(OH D was measured using competitive protein binding assay using vitamin D-binding protein as described by Chen et al. (20).

Despite the relative difficulty of predicting measured in vivo protein binding sites from DNA sequence, and relating in vivo TF binding sites to the effects of perturbing the same TFs, relating sequence elements directly to expression patterns (and vice versa) has been remarkably productive in yeast.

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