The traditional assay used to measure potency of inactivated influenza vaccines is a single-radial immunodiffusion (SRID) assay that utilizes an influenza strain-specific antibody to measure the content of virus hemagglutinin (HA) in the vaccine in comparison to a homologous HA reference antigen.
While short synthetic glycoforms with α2-3 and α2-6 siacidsaredsuitableitabligandsnds to measure potency of HA in vaccines by SPR [ 12], short glycans did not immobilize efficiently to the chemically-activated plates used for Epic® analysis (results not shown).
To measure potencies of competitive antagonists, three concentration-response curves with different antagonist concentrations were compared to a control curve (without antagonist).
The effect of CPE on Neuro-2A cell proliferation was measured to evaluate potency of the CPE.
We look at the utility and limitations of small and large animal models in measuring potency and toxicity of immunosuppressive therapies.
Thus, the last 7 chapters emphasize the traditional prophylactic measures, potency of vaccines and possibility of vaccine use, the history of vaccine improvement, recent advances in vaccine development, implementation of international control campaigns for the eradication of RP and PPR by using vaccine, and a brief overview of the pathogenesis and eradication of measles virus.
While all of these assays are undoubtedly valuable tools to identify and measure the potency of potential TBDs, none of them measure the desired endpoint of a TBD, namely, the reduction in the number of new malaria infections in the target vertebrate population (13).
To better measure the potency of sEH inhibitors, a reporting ligand, 1- adamantan-1-yl -3- 1- 2- 7-hydroxy-2-oxo-2H-chromen-4-yl)acetyl) piperidin-4-yl)urea (ACPU), was designed and synthesized.
A rigorous accounting of greenhouse gas emissions would measure the potency of pollutants based on a time line that is relevant to our policy goals, not to mention the lifetime of politicians.
As application we explored the use of these recombinant viruses to measure the potency of different antiviral agents against the human cytomegalovirus.
