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The best way to eliminate model bias in X-ray crystallography is to utilize experimentally measured phase information.
In addition, including measured phase information, when available and of good quality, should make the reconstructions more robust and consistent across individual cases and improve the depth sensitivity further [ 26].
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Comprehensive comparisons between the calculated and measured phase diagram and thermodynamic data showed that the experimental information was satisfactorily accounted for by the present thermodynamic description.
By measuring phase shifts of photons and their amplitude decay (compared to a reference signal), information on the optical properties of tissue is acquired and scattering and absorption can be distinguished.
To extract phase delay for the sample only, we separately measure the reference phase information without a sample in the field of view and subtract it from the phase delays for the sample.
Here we provide the proof of principle of a novel combination of the quantitative phase information measured using a Spatial Light Interference Microscope (SLIM) [ 26, 27], with a bright field absorption measurement acquired in the Soret band.
To reconstruct the image of the sample from its diffraction pattern (either Fresnel or Fraunhofer regime), it is necessary to retrieve the phase information from the measured intensity.
More importantly, by combining the phase information with fluorescence measurements, we were able to measure the growth dependence on the cell cycle.
The original system hardware used in the SA experiment often only measured the amplitude of the returned radio waves, and phase information was not generally available.
Experimental tests on a prototype rotor confirm that both magnitude and phase information of synchronous vibration can be measured directly without additional stator-mounted key-phasor sensors.
For each gene and time course, we coupled cell cycle phase information with the standard measures of periodicity and expression to derive a new Phase-Coupled Meta-analysis measure (PCM score).
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