Moreover, possible deleterious effects of high tidal volumes on left ventricular (LV) function are largely unknown, partly because of the difficulty of measuring myocardial function independent of changes in loading conditions [ 3].
Then, we measured myocardial contractile function and mitochondrial respiration in order to determine whether mitochondrial alterations precede diabetic-related cardiomyopathy.
Nuclear cardiology, cardiovascular magnetic resonance, cardiac computed tomography, position emission computed tomography, and coronary angiography (CA) are imaging modalities that have been used to measure myocardial perfusion, left ventricular function, and coronary anatomy for clinical management and research [ 3].
It is even possible that the imaging techniques we evaluated are better diagnostic tools than CCA to begin with, since they measure myocardial perfusion which is the physiological basis of myocardial function.
Improvements in multiple measures of myocardial function, such as fractional shortening and stroke volume, have been demonstrated in all species, and in the dog, were associated with no change in myocardial oxygen consumption and thus an increase in myocardial efficiency.
In particular, there is a growing literature using local measures of myocardial function such as strain rate imaging (Yip et al., 2003; Marcucci et al., 2008) and Doppler-based measurements of heart wall velocity (Ho and Solomon, 2006; Marcucci et al., 2008; Maeder and Kaye, 2009).
Gestational age, postnatal age and ventricular size all influenced myocardial function measured by pwTDI velocities.
Gestational age, postnatal age and ventricular size all influenced myocardial function measured by pulsed wave tissue Doppler imaging velocities.
We have shown that the myocardial function measured by atrioventricular tissue Doppler velocities increased with postnatal age and were positively correlated to gestational age at birth.
Myocardial function measured both in LA and LV was assessed using speckle tracking echocardiography technique, from the apical four-chamber view as previously described [ 33, 34].
