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The measured inhibitory effect in the assay is quantified by the flux ratio of the mycobactin synthesis reaction as a function of sAMS concentration, which could be predicted by applying the developed inhibition model.
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We identified candidate markers for this purpose for olaparib (AstraZeneca) by measuring inhibitory effects of nine concentrations of olaparib in 22 breast cancer cell lines and identifying features in transcriptional and genome copy number profiles that were significantly correlated with response.
The following report is divided into two sections: a description of the establishment of the suite of three-dimensional spheroid growth and functional assays, and an exemplification of the utility of the assays to measure inhibitory effects of molecularly targeted agents.
The tests measured "inhibitory control, associative learning, reversal learning, and spatial memory".
We also measured an inhibitory effect of C. globularis on the development of filamentous algae in the water column.
We then measured the inhibitory effect induced by pure 7-T on Gr66a-Gal4/WT males using desat1 target males painted with various amounts of 7-T.
To calculate the Ki of phlorizin for E457Q-hSGLT3, we measured the inhibitory effect of phlorizin at concentrations ranging from 0.1 to 10 µM on depolarizations induced by the K0.5 of αM-glc, 0.5 mM, and plotted the inhibition as a function of phlorizin concentration (Fig. 4C).
To perform the in vitro steroid sensitivity assay we measured the inhibitory effect of Dex on phytohaemagglutinin (PHA -stimulated cytokines.
We added PP1 and PP2 (10 μ M) to lysates of primary UM tissue and of a primary UM cell line and measured the inhibitory effect of these Src inhibitors using kinase array.
To further investigate the molecular mechanisms of MME on the inhibition of NF-κB activation in LPS-stimulated BV-2 cells, we measured the inhibitory effect of MME on the phosphorylation of MAPKs, which are associated with the regulation of NF-κB pathway.
The FICI is the mathematical expression used to measure the inhibitory effect of an interaction [ 37], whereas the time-kill assay measures the bactericidal activity and killing speed of each combination tested [ 38].
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