Several behavioral tests (SNAP, beam walk, foot fault, and water maze) were used to assess functional deficits.
To determine the protective effect of the treatments, brain and serum glutamate levels, serum GOT activity, infarct volume and functional deficit were measured in the experimental animals.
Also of note, the quantitative nature of DTI provides the opportunity to correlate injury severity with functional deficits measured by neuropsychological tests and other behavioral measures.
For example, the modified Rankin score is a measure of outcome after stroke where a value of 0 is no functional deficit, and a value of 6 is dead.
In our study, the EQ-5D could also be used to distinguish between stroke patients with different functional deficits measured with the Barthel Index (BI).
Numerous studies have confirmed the sensitivity of RNFL measurement in detecting glaucoma as well as the relationship between the extent of RNFL damage and the severity of functional deficits measured with perimetry [ 5- 7].
> -wrap-foot> Somasosensation as measured with QST did not correlate with patients' symptoms or functional deficit (P > 0.062).
We also, analyzed the correlation between the measured levels, the infarct volume and the degree of neurological and the functional deficit.
Although a functional deficit was not found in the children with elevated tricuspid regurgitation velocity as measured by the six-minute walk test, there was a statistically significant decrease in oxygenation during the test.
Future studies are needed to measure the phagocytic activity of macrophages in the spleens of nBmp2NLStm mice, to determine whether there might be a functional deficit in macrophage phagocytic activity or trafficking defects [ 30].
