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The extent of fiber bias for the lower volatility, higher molecular weight compounds is not easily predicted or measured for complex mixtures.
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The combined OCR measured for complexes II plus III, both of which use ubiquinone (Q) as an electron transfer intermediate, was significantly reduced by ATZ administration.
This score allows a clear comparison of EC pairs across complexes so that one threshold can be applied across all complexes and precision can be measured for each complex and summarized overall.
The truncated ArntbHLH domain does target the E-box, as shown by Brennan [22], Chapman-Smith [27], and our group; conditions can be found such that Kd values in the nM range can be measured for this complex.
It is well known that a population measured for a complex trait through one criteria (for example, Body mass index for obesity) may actually have distinct molecular subtypes for this complex phenotype.
An even larger increase in koff of ∼130-fold was measured for mRNA UUG) complexes assembled with E144R vs WT 40S subunits (≥46 hr−1 vs 0.34 hr−1; Figure 6C,F).
Azilsartan displayed low cytotoxic effects at 150 μM concentrations in A549 human lung cancer cells but the higher effect measured for the Zn complex suggested that this compound may act as an anticancer agent.
A model based on a generalized Langevin equation explained these observations and predicted that the stiffness measured for the motor complex acting as a linker between organelles and microtubules is ∼ one order smaller than that determined for motor proteins in vitro.
The transients are normalized, and the one measured for the PCP complexes off the silica nanoparticles was shifted vertically (multiplied by 10) for clarity.
The comparison of the fluorescence spectra measured for the PCP complexes on and off the nanoparticles (Figure 4a) indicates that the coupling with the nanoparticles leaves no effect upon the spectral shape of the emission.
The mobility measurement can be converted to a rotationally averaged collisional cross-section (CCS), and it has been reported that the CCS measured for numerous protein complexes is in excellent agreement (RMSD of 3%) with theoretical CCS calculated from atomic coordinates via a corrected projection approximation (PA) algorithm.
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