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Correlating with the antimetastatic effect measured, exposure of animals to 50 mg/kg of amifostine resulted in a four-fold enhanced serum level of angiostatin above control levels.
The exposure model [ 19- 21] was based on EXPOLIS-Helsinki study [ 22- 24] that measured exposure of adult population to various air pollutants in the study area.
To this end, we measured exposure of phosphatidylserine in lymphoblasts, activation of effector caspases in striatal precursors by monitoring cleavage of the caspases substrate PARP, and DNA cleavage in primary striatal neurons by TUNEL assay.
We measured exposure of the two related cohorts to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other dioxins by analyzing 84 blood samples, which produced median TCDD toxic equivalents blood lipid values of 240 ng/kg, which are more than 30 times higher than background or normal exposure from the region.
The measured exposure of pulmonary function was classified both as a dichotomous (eg, COPD vs no COPD) and ordinal categorical variable (eg, no lung disease, restrictive disease, COPD GOLD stages I IV), using the following criteria.
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Environmental Protection Agency TEAM (Total Exposure Assessment Measurement) Studies have measured exposures of about 800 persons to 25 volatile organic compounds (VOCs) and exposures of about 300 persons to 32 pesticides.
It provides a summary of current "state-of-the-art" principles and methodology involved in measuring exposure of agricultural workers to pesticides.
However, our study shows the general limitation of accurately measuring exposure of participants, in common with all panel studies with a similar design.
However, our study shows the general limitation of accurately measuring exposure of participants as all panel studies with a similar design.
Accumulation of positive RDTs, which measures exposure of practitioners to positive results, significantly improved both adherence to test results and reliance on parasitological diagnosis.
However, different particle samplers often were used to measure exposure of commuters and at fixed sites (typically routine monitors), which made quantitative comparisons between commuters' exposure and urban background sites difficult.
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