Sentence examples for measured endpoint in from inspiring English sources

Induction of CYP1A expression is widely used as a biomarker of exposure to contaminants including PAHs and HAHs and is a readily measured endpoint in studies of the mechanisms of AHR signaling [ 65].

It is important to note that GWAS with a pharmacological phenotype as the measured endpoint in clinical samples provide more specific data related to the drug than GWAS measuring overall survival.

While for the latter category a single pharmacophore can be derived, this is not possible for cytotoxicity as a model of cytotoxicity is in effect a collection of models for each of the different toxicity mechanisms that result in the measured endpoint.

Positive control data are crucial for evaluating a laboratory's capability to detect chemical-induced changes in measured endpoints.

Three products induced responses in one or more of the measured endpoints and toxicity profiles varied markedly in intensity across products.

All the outcome measures reported were considered to be patient-oriented rather than disease-oriented, as they measured endpoints such as a reduction in migraine frequency or severity that are of clear benefit to the patient.

Many clinical studies attempt to incorporate measure of important characteristics, such as health related Quality of Life (QoL), anxiety, depressive symptoms, fatigue, addictive behaviours using Patient reported outcomes (PRO), in order to measure endpoints that reflect patient's perception of his or her well-being and satisfaction with therapy.

Strengths of this study include its randomized, prospective nature as well as the comprehensive nature of the endpoint measured, which factored in measurements of in-hospital morbidity and quality of life after discharge.

This study sought to compare devices that use actigraphy for measuring sleep endpoints in the clinical research unit (CRU) and home environment.

Few attempts to measure toxicological endpoints in California sea lions have been made [ 23, 49].

An additional requirement for validating the read-across hypothesis is that internal exposure is linked to a biological effect reflecting the primary therapeutic response, by measuring relevant endpoints in physiologically relevant tissues.