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In contrast, although RHOXF2 overexpression in A549_M2 cells provided some apparent resistance (shift in IC50 from 448 nM to 1,099 nM), the measured effect was, in fact, largely due to doxycycline (shift in IC50 from 718 nM to 1,454 nM with empty vector) (Additional file 10b).
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The reason for this was because we wanted to measure the effect of the intervention on GPs without the measured effect being artificially enhanced by the involvement of other partners, and we wished to draw conclusions specifically on the acceptance of such an intervention by this group.
If it was the same for both types of skills, one might argue that the observed general or transferable training is de facto specific and that the measured effect is just the one implicated by the sharing-argument.
These pragmatic designs often incorporate the concept of plausibility instead of probability, aiming to construct a strong argument that a measured effect is unlikely to have been caused by inputs outside a given intervention.
Part of the measured effect is undoubtedly attributable to aspecific effects (regression towards the mean).
The potential for the sex of the infant to modify the measured effects was assessed via interaction terms between sex and the natural log of the LEMs of PCBs, p,p′-DDT, and p,p′-DDE in the multiple logistic regression models.
The measured effects are averages across 100 randomly generated instances of N items.
Prior to introduction of NPs, cells were slowly weaned to the 10, 25, or 50%% serum conditions through the course of multiple passages in order to ensure that measured effects were not due to cellular shock from a new environment.
The addition of ADP caused a significant Ca2+-sensitization of muscle fibers from all surgery groups, although the measured effects were not significantly different between groups.
This method first computes drug-induced effect using the Hill equation: E = E max × C n IC 50 n + C n, where E is the measured effect; C is the drug concentration; Emax is the full range of drug effect, usually at or near 100%; IC50 is the drug concentration producing the median effect of 50%; and n is the curve shape parameter describing the steepness of the concentration-effect relationship.
When the conductance value was identical to the measured value, the effect was very modest (Fig. S6).
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CEO of Professional Science Editing for Scientists @ prosciediting.com