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Here we also found evidence of decreased copper supply to SOD1 via CCS in diabetic myocardium, which could lead to the measured deficiencies in SOD1 activity.
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Two specially designed probes with diameters of 150 and 250 µm (Deppeler, Rolle, Switzerland) were used to measure deficiencies at the restoration margin, using the FDI criteria.
Other safety biomarkers focusing on idiosyncratic safety issues most often measure enzyme deficiencies and immune response (e.g. HLA genes).
Ferritin was used to measure iron deficiency because it has the highest sensitivity and specificity to detect iron deficiency in those without inflammation in comparison to bone marrow biopsy.
Measuring the deficiency in hospital-based studies may underestimate the true magnitude of the problem, because patients in a haemolytic crisis may increase their number of peripheral reticulocytes with normal G6PD values, thereby leading to a false-negative screening for G6PD deficiency.
Given the anomalous cone spectra, the reduction of error score on the CHT after color compensation was measured in each deficiency degree.
Systematic review of all diagnostic accuracy studies published since 1979 using clinical criteria to predict insulin deficiency (measured by C-peptide).
Vitamin D deficiency (measured as 25(OH D < 20 ng/ml) was significantly higher in the CSU group than the control group.
(i) The clinical features assessed to predict C-peptide levels; (ii) the sensitivity and specificity of clinical features as measured against insulin deficiency as determined by C peptide.
The prevalence of iron deficiency measured at baseline was 43.1% (28/65) in 2007 and 58.1% (18/31) in 2008 with a similar prevalence between the CQ/placebo groups within each year (data not shown) and in both years combined.
The main objective will be to systematically review and synthesise the medical literature to establish clinical criteria that predict the subsequent development of absolute insulin deficiency (measured by C peptide) seen in Type 1 diabetes.
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