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Future studies could be strengthened by including a) assessment of the correlation of blood lead measurements with cumulative exposure as measured by bone lead; b) assessment of whether Helicobacter pylori infection is associated with higher blood lead levels; and c) evaluation of genetic susceptibility factors, such as polymorphisms in the δ-aminolevulinate dehydratase (ALAD) gene.
Cabozantinib, an experimental drug being developed by Exelixis, seems to be able to virtually eradicate bone metastases in some patients, at least as measured by bone scans, something no other drug has done.
Assessment of parathyroid tumor biochemical behavior may be a useful predictor of disease severity as measured by bone mineral density in patients with PHPT.
Bone resorption was measured by bone histomorphometry.
Both treatment modalities led to significant bone fill measured by bone sounding after 6 and 12 months compared to baseline.
Five of the 10 patient samples had extensive amounts of bone as measured by bone volume (BV).
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The increase in bone mass was associated with increased bone formation measured by serum bone formation markers, P1NP and surface-based bone formation rate, BFR/BS.
The SIS ratio was measured by both bone scintigraphy and bone SPECT/CT.
The ratio between the entire SI joint and sacrum (SIS ratio) was measured by both bone SPECT/CT and bone scintigraphy.
That the continuous remodeling process of bone formation and bone resorption can be measured by biochemical bone turnover markers is well-established; however, due to their substantial intra-subject variability, it remains controversial whether these indices are useful in the clinical setting.
O. Louis et al. compared MRI-derived bone mineral density (BMD) measured by advanced Bone Analysis Applications software and biomechanical tests.
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