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Different models are designed to detect and measure specific artifacts or impairments [2].
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So these data cannot be attributed either to "cell specific artifacts" or due to a "transformed status".
All valorization processes start with the detection of a value in a specific artifact.
To exclude aligner-specific artifacts, we included ProbCons (black line, Figure 2) into the analysis.
Thus, platform-specific artifacts are controlled for.
To counteract disparities in duplication rate and potential allele-specific artifacts, only unique reads were used.
It should be noted that both EBV transformation and cell line-specific artifacts can affect gene expression patterns (45– 45).
The global approach allows identification of the most relevant pathways, and the cross-platform validation protects against platform-specific artifacts.
Reversed-dye labeling of the samples was always used to minimize the effect of dye-specific artifacts.
All experiments using the chimera were performed with two different tagged constructs, reducing the possibility of tag-specific artifacts.
Thus, we concluded that this weak HA activity was a non-specific artifact of using highly concentrated virus.
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