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As a measure of potency, we will refer to EC50 hereafter.
Given that high intra-family PCAIN correlation scores and low inter-family PCAIN correlation scores are necessary for defining a refined fold signature with high SNR, the difference between these two scores provides a reliable measure of potency.
The consequent sustained reductions in Isc exhibited an EC50 of 5.7 μM (2.2 14.6 μM) in WT mouse colon, consistent with a previous measure of potency at mouse Gpr119 receptors (7.9 ± 0.7 μM) (Overton et al., 2006).
RPFs for all like-acting chemicals are scaled relative to chlorophos by calculating the ratio of a common measure of potency, such as the dose concentration (U.S. EPA 2000).
Similar(56)
Three measures of potency are explored and shown to be highly correlated.
We find that classical measures of potency such as the IC50 may be functions of viral life-cycle kinetics.
However, other measures of potency, such as area under the curve (AUC), were not considered to see whether increasing the binding rate resulted in increased potency in general.
The oil/gas partition coefficient or the lipid solubility of an inhalational anaesthetic is a measure of its potency: a high lipid solubility means high potency but also a longer emergence time [ 6, 20].
Subjects were given one of the three daily doses (100IR, 300IR or 500IR) of the SLIT tablets [IR is a measure of biological potency (skin reactivity) used to describe the strength of an allergen extract].
Using these values as a measure of relative potency, Table 2 demonstrates that maximum response to a sample can differ for samples with similar relative potency.
The minimum concentration of P22sTsp which resulted in detectable cell agglutination (minimum agglutination concentration) was determined and used as a measure of agglutination potency of P22sTsp.
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