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First, site-specific biases, such as conservation, may artificially conflate the coevolutionary measure of functionally relevant residues.
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This highlights the complex nature of measures of functionally relevant similarities in proteins.
Clinically these data indicate that the initial forward destabilizing displacement is increased, while the subsequent backward displacement (a measure of the functionally corrective braking action of LLR) is delayed.
The Expanded Timed Get Up-and-Go (ETGUG), a reliable clinical assessment, measured time series of functionally important tasks using a multimemory stopwatch [ 25, 26].
While musculoskeletal problems are leading sources of disability, there has been little research on measuring the number of functionally limiting musculoskeletal problems for use as predictor of outcome in studies of chronic disease.
The positional AEVs measure the average distance of functionally defined sets.
The ECP algorithm provides a discrete mathematical measure of pairwise distances of functionally related aligned sequence sets.
Selfed seeds of T. turgidum× Ae. tauschii haploid hybrids usually result from the union of unreduced gametes (Matsuoka et al. 2013), and the level of seed setting was therefore used as a measure of the production of functionally unreduced gametes.
Incorporation of subunit 5 (A or B) is essential for the stable expression of optically detectable functional C cO [ 20, 39] and hence the level of detectable C cO is a direct measure of the level of functionally incorporated subunit 5.
§The test statistic D n measures whether the distribution of functionally related genes is random in gene clusters.
Measures can be base measures, i.e., measures that are functionally independent of other measures, or derived measures, which are defined as a function of other measures.
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