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Sample sizes vary in some cases, where there was insufficient sample to measure multiple steroids (e.g., some blood samples were greater than others, and could be assayed for more steroids).
The reported capillary electrophoresis method is amenable to the limited sample volume generated by individual zebrafish and provides a rapid means to measure multiple steroids in the large number of samples required for toxicity testing.
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With the use of a method to identify multiple steroids simultaneously, altered steroid levels are rapidly identified in individuals.
Multiple steroid hormones can now be accurately measured by tandem mass spectrometry in a single sample.
One patient with juvenile rheumatoid arthritis had multiple steroid injections in each knee.
Furthermore, they stated that it would be better justified for a future controlled trial to compare multiple steroid injections with systemic steroids or a different steroid injection regime.
Among concomitant anti-TNF and steroid users, 43% had multiple steroid courses spanning >3 months while receiving anti-TNFs.
However, multiple steroid cycles may cause adrenal insufficiency or osteoporosis in mothers [49].
Most studies measured multiple response variables.
All studies measured multiple outcomes.
These were not scaled to measure mortality, thus steroids were not recommended on this basis.
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