The results emphasise the need to measure multiple domains of functioning, and show that the connections between pain, physical disability and adaptive functioning are looser than might be predicted.
Widely used questionnaires in this setting include questions that measure multiple domains of CINV such as the severity, the perceived intensity of CINV; frequency, the amount of times CINV occurred over a time period; duration, the length of time that these symptoms persisted; and distress, the perceived burden that these symptoms place on the patients daily function and QoL [ 29].
In 2009 an expert panel concluded that neuropsychological test batteries aimed at measuring multiple domains of cognitive function are generally more reliable than single tests, and tend to be more strongly correlated with functional status.
Subjects were administered a comprehensive neuropsychological battery that measures multiple domains of cognition (Table 1).
The Stroke Specific Quality of Life Scale (SS-QoL) was developed specifically to measure quality of life in stroke trials, measuring multiple domains of quality of life as well as providing a global score (Williams et al., 1999).
Two of the fibromyalgia trials assessed fatigue as a secondary outcome by using the Multidimensional Fatigue Inventory (MFI) [ 11], which measures multiple domains of fatigue on five scales: General Fatigue, Mental Fatigue, Physical Fatigue, Reduced Activity, and Reduced Motivation.
It is a self-administered questionnaire that measures multiple domains of fibromyalgia symptoms and functional impairment, and it contains 20 questions that assess the following areas: physical functioning, overall well-being in the previous week, days of work missed, and symptoms of pain, fatigue, morning tiredness, stiffness, job difficulty, anxiety, and depression.
Health literacy (HL) is a measure of multiple domains including: reading fluency, ability to locate and use information and do simple mathematical tasks.
The authors compared persons with scores above and below a predetermined threshold on the Center for Epidemiological Studies Scale for Depression (CES-D) with nondepressed (ND) persons on measures of multiple domains associated with successful aging.
Most neuropsychological (NP) tests require a number of cognitive processes and, therefore, measures of multiple domains.
Pediatric health-related quality of life (HRQL) measures explore multiple domains of HRQL.
