Sentence examples for measure lysosomal function from inspiring English sources

We therefore used another independent method to measure lysosomal function in macrophages.

Self-quenched BODIPY dye conjugated to bovine serum albumin labelling was performed (DQ-BSA; Molecular Probes, Invitrogen, USA), in order to measure lysosomal function.

In order to measure and compare lysosomal function in these cell lines, we employed the long lived protein degradation assay using specific pharmacological inhibitors to discriminate between the different forms of lysosomal degradation.

In this regard, our results validated that TFEB, the major regulator of lysosomal biogenesis, facilitates or rejuvenates microglial capability in degradation of fAβ and amyloid plaques by upregulating lysosomal quantity and enhancing lysosomal function.

The accumulation of lipid hydroperoxides within the lysosome might therefore compromise lysosomal function.

Growing evidence indicates that lysosome positioning in cells can modulate lysosomal function.

CQ (Sigma, USA) was used to block lysosomal function, and the later degradation stage of autophagy was used to measure autophagic flux in cells.

ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function.

Luciani, A. et al. Impaired lysosomal function underlies monoclonal light chain-associated renal Fanconi syndrome.

A primary interest of our lab is to define lysosomal function in neurodegeneration.

Thus, TFEB is primarily responsible for BRAFi-associated transcriptional activation of autophagy and lysosomal function in melanomas.