Sentence examples for measure functional importance from inspiring English sources
We measure functional importance by measuring the extent of negative selection acting on the protein, which is defined here as ρ0(1 − ω0).
Strength of purifying selection can be used as a measure of functional importance of the gene under the assumption that more important genes are less tolerant to missense and nonsense substitutions.
And while recurrence is often the surrogate measure of functional importance, the four unique driver candidates from this 15 patient sample still contain features associated with oncogenic gene fusions.
In this paper we advance the measure of the functional importance of ESPs provided by natural areas and permanent cultivations based on their effectiveness at performing the services.
These findings are consistent with the idea that the density of potentially functional polymorphisms can be used as a measure of the functional importance of a gene.
It quantifies the degree of long-term natural selection against amino acid change and is a measure of the functional importance of the position [ 27, 32- 34].
The overall decrease in network efficiency was paralleled by a stronger betweenness centrality of ipsilesional M1, the latter being a measure of the functional importance of a node for information processing.
Understanding the role of gene pleiotropy in the map from genotypes to phenotypes has been one of the central topics for biologists, which refers to the phenomenon of a gene affecting multiple traits As a major measure for the functional importance of a gene, this concept has played a fundamental role in genetics, development, and evolution (see [ 1– 3] for recent reviews and comments).
We measure a gene's functional importance in relation to cell survival by the essentiality of the essential genes and the toxicity modulation degree of non-essential genes.
Relative conservation of SLiMs was measured to assess their functional importance.
To make use of this observation, we assign a score or weight to each node and edge of a PPI network using an iterative minimum-degree heuristics algorithm, measuring the topological and functional importance of a node (i.e., the likelihood of being a hub or bottleneck) and an edge in the PPI network with respect to the global network topology.
