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Generally, respondents with IRD report relatively greater deficits in the scales that primarily measure functional disability, i.e., physical functioning, role limitations due to physical function, bodily pain, general health, rather than the scales measuring a construct of mental health, i.e., mental health, role limitations due to emotional health, social functioning, and vitality.
The Oswestry Disability Index (ODI) is the most commonly used disease-specific patient-reported outcome tool to measure functional disability related to back pain.
Phase B ADT-Worseners and ADT-Non-worseners were also assessed using the Sheehan Disability Scale (SDS) to measure functional disability in work, social, and family life.
This was to provide a validated instrument to measure functional disability and health-related quality of life in patients with osteoarthritis of the knee in Iran.
The Bath Ankylosing Spondylitis Functional Index (BASFI) was developed more than a decade ago to measure functional disability of patients suffering from Ankylosing Spondyltis (AS) [ 1] and subsequent outcomes following therapy.
The Disease Activity Score-28 (DAS28) was used to assess clinical disease activity [ 25] and the anglicised version of the Stanford Health Assessment Questionnaire HAQQ) [ 26] to measure functional disability.
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The Sickness Impact Profile (SIP) [ 20] measures functional disability in different areas of daily functioning.
The QBPDS, more specifically, measures functional disability in persons with back pain.
First developed in 1965, it measures functional disability by quantifying patient performance in 10 activities of daily life.
For example, a multi-item scale measuring functional disability and a single general question on functional disability might not evoke the same associations in the patient being questioned.
Well-accepted PRO measures used in RA clinical trials include the HAQ-DI (which measures functional disability), the SF-36 (a generic HRQoL measure), and various pain assessments.
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