Your English writing platform
Discover LudwigExact(4)
There is a complex lesion in the gallbladder fossa, which demonstrates a measurable soft tissue component with a peripheral myxoid degeneration.
Bone lesions were considered measurable only if a measurable soft tissue component were present.
Radiographic responses and progression were assessed using RECIST 1.1 in patients with measurable soft tissue disease (Eisenhauer et al, 2009).
However, early studies in the pre-PSA era often relied on acid phosphatase levels and patient symptoms as markers of response, as only 20% of patients with metastatic prostate cancer, have measurable soft tissue disease (Figg et al, 1996).
Similar(56)
With regard to the selected RECIST 1.1 criteria, we handled bone metastases as non-measurable lesions as all of the bone metastases being present in the patients examined by our study show no measurable soft-tissue component.
The doses and scheduling of the taxanes vary between studies, but the end points of PSA response and response of measurable soft-tissue metastases were similar; the latter applies to only a minority of the patients enrolled on these studies.
Measuring tumour response in clinical trials of hormone-refractory prostate cancer has been problematic as few patients have measurable soft-tissue disease and the majority of patients have metastases to bone, a location that is difficult to assess for defining tumour response.
The evaluation of new agents in metastatic prostate cancer by the Genito-Urinary Group of the European Organisation on Research and Treatment of Cancer EORTC GU Groupp) has taken the form of a series of Phase II studies using measurable soft-tissue metastases as indicator lesions.
Responses were observed in all measurable metastatic sites (soft tissue, liver and lung).
Moreover, this study showed that 12 of 32 evaluable patients (37.5%) showed a decline in serum PSA after vaccination, and 2 of 12 patients with soft tissue metastases exhibited a measurable decrease in index lesions by CT [ 22].
Soft tissue component was also measured separately.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com