Sentence examples for measurable endpoints from inspiring English sources

However, the measurable endpoints available to risk managers, at least for vertebrates, are typically laboratory tests.

These reporting requirements will provide clarity on the the test chemical, experimental design and conditions, chemical identification, test organisms, exposure confirmation, measurable endpoints, how data are presented, data availability and statistical analysis.

These environmental indicators are benchmarks for the current conditions of the Great Lakes coastal region and provide measurable endpoints to assess the success of future management, conservation, protection, and restoration of this important resource.

Thus a large variety of measurable endpoints can be biomarkers, including clinical laboratory results, data from disease-specific diagnostic tests, in vivo imaging results, and data from intervention-specific assays designed to capture pharmacodynamic responses to treatment.

Thus, there are at least two processes, with different measurable endpoints, that operate at the cellular level to ascertain NK cell tolerance.

This is because data are derived from measurable endpoints, whereas if incubation periods were to exceed natural lifespan of the host it would only be possible to define the clinical endpoint by extrapolation of the observed data.

The objective of the current studies is to provide a framework for modeling cellular signaling processes beginning at a plasma membrane receptor and ending with a measurable endpoint in the signaling process.

This measurable endpoint, typically the production of a colored reaction product, is usually detected spectrophotometrically and the absorbance of the reaction product is used to quantify the amount of antigens or target species present in the sample.

New thinking will be required to modify clinical trial design, and to consider biomarkers that relate to invasive and metastatic phenotypes, for example as in trials with denosumab where the development of skeletal-related events (SRE) was an accepted and measurable endpoint [ 221].

As these theories identify the proximal predictors of behaviour they provide measurable interim endpoints that represent actual behaviour (usually intention).

Although simultaneous parameter fitting and full parameter identifiability could not be accomplished in this context, the updated model fulfilled the Agoram 25 criteria: (i) Fit for purpose: only compartments and parameters that were necessary to improve predictions of specific measurable clinical endpoints were added to the model.