Sentence examples for measurable defects in from inspiring English sources

Overexpression of APP/BACE-1 resulted in the progressive and measurable defects in morphology of eyes and locomotion.

In general, microtubule defects in mtr1Δ cells were very subtle, with no measurable defects in spindle formation or elongation (data not shown).

Evidence suggests that lower extremity injuries, particularly lateral ankle sprain, lead to impaired lower-extremity proprioception and measurable defects in postural stability.

This data suggests that peripheral blood cells in AD patients display measurable defects in mitochondrial respiration, dNTP pool balance, and BER activity.

The clinical phenomenon of loss of awareness of hypoglycemia, and its associated increase in risk of severe hypoglycemia, is accompanied by measurable defects in the counterregulatory stress responses attributed at least in part to failure of central glucose sensing.

This decline in the B cell numbers is a major factor rendering HIV-infected individuals incapable of mounting an effective functional antibody response to pneumococcal polysaccharides [ 5] In addition to increased immunoglobulin secretion and a decrease in number of naïve resting B cells [ 6], HIV leads to multiple measurable defects in the B-cell subpopulations.

Finally, we failed to identify a measurable defect in double-strand break repair in Tdp1−/−, Aptx−/− or Tdp1−/−/ Aptx−/− astrocytes.

Similarly, deletions of genes involved in the Slt2/Mpk1 MAPK cascade for cell wall biogenesis (ROM2, PKH1, PKH2, YPK2, MKK2 and RLM1) are all hypovirulent or strongly hypovirulent without any measurable defect in in vitro growth.

We examined if Trol is required for the subsequent patterning of dorsal somatic lineages, but no measurable defect in Eve-specification was observed in embryos derived from trol germline clones.

The phenotype of the repressed histone expression may be manifested with a fast kinetics, before the replication stresses could bring about measurable defect in S-phase progression such as that scored by bromodeoxyuridine incorporation.

Consistent with the latter results, our experiments with APTX knockout chicken DT40 cells, APTX−/− mouse fibroblasts, AOA1 human fibroblasts, and AOA1 lymphobastoid cells also failed to detect a measurable defect in global SSBR rates [24].