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For example, PM-RA means parameter estimates of the probability-mixing model fitted to data simulated from the response-averaging model Fig. 9 Estimates of μ and σ estimated from stimulus mixture data under either the probability-mixing or the response-averaging model plotted against the estimates from single stimulus data, for 100 repetitions.
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Furthermore, we assessed connectivity gradients across the longitudinal and horizontal axes by plotting slice-by-slice mean parameter estimates.
Population mean parameter estimates were 1.41 L for volume of distribution (V) and 0.244 L/min for clearance.
Moreover, the precision of the corresponding population mean parameter estimates was relatively low, compared with the other parameters in the model.
Significant activations for the experimental contrasts of interest are summarized in Table 1, and statistical parametric maps and condition mean parameter estimates are displayed in Figure 1.
Briefly, this entails (i) defining a target steady-state INR response, in our case 2.5, and (ii) using the model to estimate the dose required to achieve the target response, conditioned on the population (mean) parameter estimates.
In Experiment 3, mean parameter estimates for RS to scenes were extracted from 8-mm radius spheres centered on the maximal voxel of each participant's scene-selective transverse occipital sulcus (TOS) and parahippocampal place area (PPA).
To determine the effect of RS on face-selective regions, mean parameter estimates were extracted from an 8-mm sphere centered on the maximal voxel in each participant's individually defined ROI using MarsBar (Brett et al. 2002).
In Experiment 4, mean parameter estimates were extracted from 8-mm radius spheres centered on the maximal voxel of each participant's lateral occipital object area (LO) and posterior fusiform object area (pFs).
For Experiments 1 and 2 addressing RS to faces, mean parameter estimates for each condition were extracted from an 8-mm radius sphere centered on the maximal voxel in each participant's face-selective occipital face area (OFA) and fusiform face area (FFA) using MarsBar (Brett et al. 2002).
Evaluation of the PK/PD model for 4βHC The posterior predictive performance of the PK/PD model was evaluated by generating predictions for the 34 subjects included in the analysis using 500 of the posterior sets of population mean parameter estimates.
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