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However, identifying synthetic glycan B cell epitopes that induce protective immunity has traditionally been a time-consuming trial-and-error process, as predicting the immunogenicity of an oligosaccharide by means of structure alone is not straightforward.
Recent advancements in the utilization of residual dipolar couplings (RDCs) as a means of structure validation and elucidation have demonstrated the need for, not only a more user friendly, but also a more powerful RDC analysis tool.
The set of information units was then transformed into a bipartite graph, and analysed by means of STRUCTURE, an application aimed at grasping the structure of the relations among a set of "objects".
Individual ancestry estimates were assessed using an unsupervised assignment of individuals to populations by means of STRUCTURE 2.2 [48].
Using PC scores and, alternatively, individual admixtures obtained by means of STRUCTURE, we have shown that there is a potential benefit of correcting for population stratification in Spanish studies including samples from Canary Islanders.
For comparisons of means of structure diameters, two-tailed unpaired t-test was used.
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By means of structure-based bioisosterism, triazolone was used as a new bioisostere of oxygen atom.
By means of structure-based bioisosterism approach, a series of novel purinylthioacetanilide derivatives were designed, synthesized and evaluated as potent HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs).
By means of structure-based molecular hybridization strategy, a series of novel diarylpyri(mi dine derivatives targeting the entrance channel of HIV-1 reverse transcriptase (RT) were designed, synthesized and evaluated as potent non-nucleoside reverse transcriptase inhibitors (NNRTIs).
Data were collected by means of structured interviewing from a variety of faculty within the School.
Factor A points to a means of structuring activities, mainly characterized by simplified execution of the managerial function cycle.
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