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In NHANES III, laboratory measures were within 10% of reference means for urinary cadmium (r = 0.97) (Paschal et al. 2000).
Additionally, in an external quality assurance program from the Center of Toxicology of Quebec, laboratory measures were within 10% of reference means for urinary cadmium (r = 0.97) (Paschal et al. 2000).
The adjusted geometric means for urinary BPA excretion decreased with decreasing levels of eGFR (p for trend = 0.04).
We also found that the adjusted geometric means for urinary triclosan excretion decreased with decreasing levels of eGFR regardless of the equation (p for trend < 0.01 and 0.01, respectively, for MDRD Study and CKD-EPI equations).
The adjusted geometric means for urinary BPA excretion decreased with decreasing renal function using the MDRD Study equation, from 2.46 ng/mL for those with normal renal function to 2.31 ng/mL for those with mildly decreased renal function, and to 2.04 ng/mL for those with CKD (p for trend = 0.04).
When we used the CKD-EPI equation, the adjusted geometric means for urinary BPA excretion still decreased with decreasing renal function among females, from 1.90 ng/mL for those with normal renal function to 1.81 ng/mL for those with mildly decreased renal function, to 1.57 ng/mL for those with CKD, but the trend was not statistically significant (p for trend = 0.29).
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Geometric means for maternal and child urinary concentrations of BPA were 1.96 and 3.94 µg/L, respectively.
For persons with diabetes, the geometric mean for urinary cadmium with albuminuria was 61% higher than for those without albuminuria.
The mean for urinary Cd between study respondents showed the sign of increasing body burden resulting from an environmental exposure.
Proteinuria was observed in the EVR+Reduced TAC group, but maximum mean values for urinary protein to creatinine ratio were below even the conservative threshold of 300 mg/g, and preexisting cases of proteinuria were not aggravated.
In healthy subjects given a 50 mg oral dose of tramadol, the mean values for urinary excretion over 24 hours (expressed as a percentage of the dose administered) were tramadol 12%, M1 15%, and M2 4% [ 34].
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