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The discovery of this cryptic Shp2 allosteric site may provide a means for targeting Shp2 activity with high specificity and suggests that buried-yet-targetable allosteric sites could be similarly uncovered in other protein families.
Non-spherical particles have also been found to exhibit distinct in vivo distribution profiles, which may provide a new means for targeting of specific organs or tissues, such as the spleen [42], the lungs [43], and tumor tissues [44, 45].
However, optimal means for targeting HO-1 or delivering its products remain to be determined, and functional data demonstrating efficacy in man are very limited.
In conclusion, MSCs transplantation reverts hyperglycimia and kidney-targeted transplantation of MSCs mediated by UTMD increases MSCs homing to damage renal tissue in diabetic nephropathy rats and prevents nephropathy, therefore providing a potential means for targeting therapeutic agents to kidney.
As we and others move into using selected reaction monitoring as a means for targeting specific proteins, the MS/MS data presented in the Honey Bee PeptideAtlas will provide the empirical evidence required to make intelligent decisions about the design of these experiments.
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Non-executable files are especially popular as a means for targeted attacks.
Encapsulation in protease-resistant, ROS-permeable carriers targeted to endothelium prolongs protective effects of antioxidant enzymes, further diversifying the means for targeted modulation of endothelial ROS.
Folic acid has been investigated over the past two decades as a means for targeted delivery of payloads to tumor cells.
The possibilities that the aberrations predict organ dysfunction and reveal novel means for targeted therapy warrant further studies.
To increase the visibility of in-class studies among interested researchers and to strengthen their impact on student learning, we have extended the typical model of inquiry-based labs to include a means for targeted dissemination of student-generated discoveries.
These considerations imply that genome-based student research models with means for targeted dissemination have strong future potential to benefit a wide range of model organism research in ways that mutually benefit undergraduate education.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com