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Signals transmitted via cell-cell contact provide an alternative means for regulating early stage synaptogenesis.
The canonical model of Wnt signalling requires that N-terminally phosphorylated β-catenin is targeted for destruction, thus providing a means for regulating the transcriptionally active protein.
Activating (FcγRIIa, FcγRIIIa and FcγRIIIb) and inhibitory (FcγRIIb) FcγRs are frequently coexpressed on the same cell, thus providing a means for regulating signalling thresholds [ 5, 6].
This raised the possibility that axonal microRNAs may be a feature of mRNA translational regulation and hence, provide alternative means for regulating axon regeneration (Hengst et al., 2006).
When the Pennsylvania Turnpike, the first modern toll superhighway, was completed in 1940, I.B.M. punch cards proved the only practical means for regulating tolls according to distances from exit to exit.
Allostery is an essential means for regulating biomolecular functions and provides unique opportunities for drug design, yet our ability to elucidate allosteric mechanisms remains limited.
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However, regulating the here described Brk1 trimeric pool or Brk1 incorporation into the Wave complex might provide a means for cells to regulate the assembly of Wave complexes.
The existence of this Brk1 precursor might offer a means for cells to regulate their rate of Wave complex assembly, even though in HeLa cells Brk1 trimers constitute a major pool [11], and are therefore probably not limiting the rate of Wave complex assembly.
This provides a possible solution to the aforementioned problems with the Cln3 protein synthesis rate sizing mechanism, as well as a means for ploidy to regulate size control directly.
Additionally, because dashboards allow users to control the extent and content of information displayed, they provide a means for users to self-regulate information exposure and avoid overload in the face of large amounts of information [ 22].
Tyrosine phosphorylation of NPxY motifs can also protect integrin tails from calpain cleavage, as has been shown for β3, providing another means of regulating integrin tail availability for cytoplasmic interactions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com