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The path ahead is not binary: instead there is a spectrum of possible outcomes, from a mostly symbolic break with Europe (the soft end), to a much more meaningful separation (the harder edge).
The term "Big Four" has become standard usage with Djokovic, Rafael Nadal, Federer and Murray routinely reaching the latter stages of Grand Slam tournaments, hoarding the next-tier Masters 1000 titles and creating meaningful separation with the best of the rest, like David Ferrer, Jo-Wilfried Tsonga, Berdych and Mardy Fish (the four other men who have qualified for the finals in London).
Tables 3 and 4 also clearly show that, in general, there is no clear statistically meaningful separation across assays or assay category type using a single conformer per compound.
A 0.3 μm pre-column inline filter (Agilent Technologies, Palo Alto, CA, USA) was used to minimize potential contamination to the MS system; the pre-column inline filter did not provide meaningful separation.
Stewart's primary win was another crack in the facade that there was a meaningful separation between the hard right wing and the mainstream Republican Party.
Indeed, there is already alarming evidence that Trump's children are too involved in his business and official presidential responsibilities to provide any meaningful separation of the family business from state duties.
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Finally, we do not account for severity of depression since the HSCL-D tool does not allow for clinically meaningful separations in depression severity.
Is it sufficient to use only a single conformer per compound and still realize a statistically meaningful difference or separation between the 3-D similarities of reputed actives and inactives from a biological test?
The second part of this study examines the question: is it sufficient to only use a single conformer per compound and still realize a statistically meaningful difference or separation between the 3-D similarities of reputed actives and inactives?
This difference in median TSW may not appear clinically meaningful, however, a separation of the Kaplan Meier survival curves is observed beyond 6 months, which is likely to explain the statistically significant difference between the two treatments.
In cases where the differences between the number of wrong decisions is too low for a meaningful comparison, the model separation, ΔTS is more informative.
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