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But Mr Nemes is creating a meaningful difficulty.
At the time this study was conducted no data were available regarding whether a particular score with these questions constitutes a threshold for clinically meaningful difficulty with coping strategies.
As the categories are only useful if they have a meaningful hierarchy of difficulty these disordered categories were collapsed until all categories were correctly ordered in hierarchies of difficulty.
Further difficulties for meaningful comparisons are different numbers of training bulls and that no information about the additive-genetic relationships between training and validation bulls was provided by the other authors.
"Quite frankly, I think they were having difficulty doing meaningful science with the existing configuration," Mr. Boehlert said.
In the current economic climate, many companies are having difficulty generating meaningful increases in either revenue or profits.
However, suffering from the cyclic variability of combustion, it is difficulty but meaningful to control mean of combustion phase and constrain its variance.
On balance, economic, political and social difficulties will prevent meaningful change in the near term.
It is not uncommon that researchers face difficulties when performing meaningful cross-study comparisons for research.
The language in the more recent letter was much more conciliatory, acknowledging the difficulties of enacting meaningful political change within China while also emphasising that signing the ICCPR would be a "feasible" goal for Chinese leaders.
Although it is logical that definitive evaluation of new therapies should be based on clinically meaningful outcomes, there are major difficulties to overcome when conducting treatment trials in multiple sclerosis (MS) with clinical endpoints such as relapse rate or progression in disability.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com