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Mean weight change was 2.0 ± 1.2 kg.
Data extracted from each of the studies for the meta-analysis included the number of participants per group, the mean weight change in kilograms from randomization to study completion of the exercise intervention for each group, and the standard deviation for each mean.
Among more recent studies, mean weight change over one year in one double-blind study of lithium-treated patients was 4.2 kg (Calabrese et al. 2003).
Open image in new window Fig. 2 Mean weight change of the third-instar larvae of Helicoverpa armigera Hübner exposed to different concentrations of Bacillus thuringiensis isolate with or without 1.0% MgCl2 salt.
Fig 3 Mean weight change at course locations where weights were obtained for those with either cramping or near cramping (closed circles and solid lines) and those without cramping (open circles and dashed lines) during the race segment ending where weight was measured (upper graph) and during the subsequent course segment (lower graph).
The mean weight change for each 1 kcal/g ED was −42 g/year [95% confidence interval (CI): −112, 28].
The mean weight change was +0.26 kg (SD 2.02) with a median change 0 kg.
We therefore cannot interpret mean weight change across different time points as a trajectory.
Rates of hypoglycaemia and mean weight change were comparable between the treatment groups.
Overall mean weight change for the whole group was −1.85 ± 4.6 kg, P < 0.01.
The primary outcome is mean weight change between baseline and 3 years.
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