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Cumulative erythropoietin dose was categorized as follows: mean weekly dose administered between days 0 and 14 (14d) after initiating CHD; mean weekly dose administered between days 14 and 90 (90d); and mean weekly dose administered between days 90 and 180 (180d).
The mean weekly dose of methotrexate used in this study was 9.5 mg per treatment episode.
The primary outcome (DCR) for each patient was calculated as the mean weekly dose of PEG-Epo during the post-switch EP divided by the mean weekly dose of DA during the pre-switch EP.
The geometric mean weekly dose of DA was 23.2 μg (95% CI 20.6, 26.3) in the month prior to switch.
No significant differences were reported in the mean weekly dose of rHu-EPO and Darbepoetin in both the CKD groups (data not shown).
In those receiving ESAs, there were no differences in the mean weekly dose between stages 3 and 4 CKD (Table 5).
Similar(37)
Mean weekly doses of paricalcitol above 15.0 ug were associated with an 18% reduction of mortality risk.
Kalantar-Zadeh et al. reported patients treated with mean weekly doses of 1.0 ug to 5.0 ug of paricalcitol.
Patients received mean weekly doses of methotrexate/placebo ranging from 15.2 to 15.9 mg/week and 15.8 to 16.3 mg/week for the tocilizumab plus methotrexate and tocilizumab plus placebo groups, respectively.
Mean and median weekly dose generally decreased with decreasing administration frequency, though the case mix in the three groups was different.
The average mean (SD) weekly dose of darbepoetin alfa administered during the entire study was 151 μg/week (SD = 62) to ESA-naïve patients and 174 (58) μg/week to prior ESA-treated patients.
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mean weekly blood
mean weekly maximum
mean weekly cholecalciferol
mean weekly text
mean weekly online
mean weekly work
mean weekly dosage
mean weekly erythropoietin
mean effective dose
mean weekly incidence
mean weekly quantity
mean weekly frequency
mean weekly alcohol
mean weekly exercise
mean weekly consumption
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