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Change was defined by adjusting for the baseline scores of the EQ-5Dindex [ 22]; in this way, regression to the mean was corrected simultaneously.
Overdispersion larger than 1.5 (i.e. the variance in a GLM with Poisson distributed errors was at least 1.5 times larger than the mean) was corrected by multiplication of standard errors with the overdispersion parameter Φ, using a quasi-GLM model or a model with negative binomial distribution of errors (Zuur et al. 2009).
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For epidermal thickness, group means were corrected for the respective untreated, contralateral skin because of an existing systematic difference in overall epidermal thickness between the groups.
Means were corrected for sex, age and education level.
Means were corrected for sex, age, marital status and education level.
The mean viability was corrected for potentially confounding covariates by least squares regression and estimation at the sample means for each covariate.
The mean HEA was corrected from 81.6 ± 8.2° (pre-op).
The mean SUV was corrected for the body weight of the patient.
Additionally, the mean SUV was corrected for partial volume effects by applying recovery coefficients obtained from phantom studies [ 25].
This mean value was corrected for the background level as described above and normalised to 1 μM BPD-MA control solution.
The mean injected activity was corrected for the mean residual activity after administration.
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