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The CN54gp140 liposomes were evaluated for mean vesicle diameter, polydispersity, morphology, zeta potential and antigen encapsulation efficiency before being incorporated into hydroxyethyl cellulose (HEC) aqueous gel and subsequently lyophilised to produce a rod-shaped solid dosage form for practical vaginal application.
Expression of either prion protein led to an increase in mean vesicle diameter in both types of boutons compared with their UAS controls (Fig. 3D, * P < 0.05, Student's t-test, n = 4 10 boutons).
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The size distribution of the NVs and of exosomes was measured using a Malvern Zetasizer, and the results revealed mean vesicle diameters of 141.2 nm and 105.4 nm (Fig. 2B), respectively, which were similar to the mean diameters measured with TEM (Fig. 2A).
A Student's t-test was performed to assess the significance of the increase of the mean of the vesicle diameter distribution after Ca2+ addition.
The parameter characterising the synaptic vesicles is their diameter, which is set at a mean diameter of 35 nm and a standard deviation of 10 nm; see Figure 10(b) for a vesicle diameter distribution.
The prepared formulations were characterized in vitro for vesicle morphology, mean vesicle size, and percent drug entrapment.
Indeed, the square root of triskelions number versus inner vesicle diameter roughly follows a straight line.
(E ) Cumulative vesicle diameter in acetylcholine neurons.
We also quantified synaptic vesicle diameter for several synapses.
B Mean vesicle size with standard deviation.
A Mean vesicle count with standard deviation.
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