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Ventilation parameters [ΔP, Pplat, mean ventilation pressure (Pmean), PEEP, VT, pCO2, pH] from 3 days preceding pECLA device implant until 3 days afterward were compared.
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At the end of ventilation, mean arterial pressure (MAP) and gas analysis were evaluated in all ventilated groups.
With respect to the ventilator strategies, it has been demonstrated in different animal models that for the same peak or mean airway pressure, ventilation with PEEP at lower tidal volumes results in less edema than would occur with ventilation using zero PEEP and ventilation with higher tidal volumes.
Detailed baseline and echocardiographic parameters of the cohorts are described in Tables 1 and 2. The three cohorts differed in their severity of hypercapnia, use of mechanical ventilation and mean airway pressures during mechanical ventilation, but were comparable in all other characteristics.
CMV, controlled mechanical ventilation; MAP, mean arterial pressure; PaCO2, arterial partial pressure of carbon dioxide; ]PaO2, arterial partial pressure of oxygen; PSV, pressure support ventilation.
Measurements and Main Results: Preoperative (age, hematocrit, relative perfusion of the nondependent lung) and intraoperative (PaO2 during 2-lung ventilation and mean arterial pressure at the lowest PaO2) variables were identified as independent factors affecting PaO2 in OLV.
Clinical data collected were Amikacin dosage, Body Mass Index (BMI), Mechanical ventilation (MV), mean arterial pressure (MAP), use of Noradrenaline and continuous hemofiltration (CVVH).
Secondary outcome measures included minute ventilation (MV), mean arterial pressure (MAP) and heart rate (HR).
The score included PaO2/FiO2, basal PaCO2, respiratory system compliance, minute ventilation and mean airway pressure.
No difference was found concerning ventilation pressure.
Heart rate (HR), mean arterial pressure (MAP), minute ventilation, respiratory rate, body temperature, and fractional inspired oxygen level were also recorded.
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