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Mean uptake values were calculated for each of these regions on the registered F-FDG PET images.
The mean uptake values of unaffected family members are obvious between groups 1 and 3 and this demands explanation.
Two independent raters manually segmented different regions of interest, as defined by Duvernoy in "The Human Hippocampus" [ 19], resulting in regional mean uptake values for each segment.
Mean uptake values ± SD in tumour were 2.18 ± 0.34, 1.16 ± 0.32 and 0.67 ± 0.23 in Fischer, Wistar and Sprague Dawley rats, respectively.
The mean uptake values for the operated side in the 11 patients without large defects was 4.2 (1.8), 4.0 (1.2), and 2.2 (0.9) after 1 week, 4 months, and 12 months, respectively.
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Solid curves show the mean uptake value expressed in %IA/g ± SD.
The mean uptake value within the metabolic volume is defined as SUVmean.
The standard uptake value ratio (SUVR) normalizes the uptake values to the mean uptake value within a region containing nonspecific binding, usually the cerebellar grey matter.
For the FDG PETs, the mean uptake value in the pons [ 19] was used to normalise the PET images of each subject, thus allowing for a comparable range of values.
With regard to the semiquantitative methods, some authors have proposed the evaluation of arterial SUVmax [ 24, 34, 37], while others have normalized arterial SUVmax to the background activity, represented by the mean uptake value of a selected reference structure [ 29, 35, 41].
> -wrap-foot> timeime difference between injection and probe measurements, T/B tumour/background ratio, SUV mean mean standardised uptake value in tumour obtained from [F]FDG PET or PET/CT imaging [F]FDG PET or PET/CT scanning was performed in a fasted state with glucose levels less than 120 mg/dl within 2 weeks prior to surgery.
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