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Finally, preliminary data suggest the method to be able to provide information on trabecular bone architecture such as regional mean trabecular plate separation.
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The mean trabecular branch angle becomes more horizontal.
Then, a nonlinear regression is performed for each specimen, and the mean trabecular thickness is estimated.
Mean trabecular width and percent bone area were calculated at such sites.
Although the trabecular surface was markedly irregular in osteoblastic metastases, no significant difference was found in the mean trabecular thickness (Tb.Th) between osteoblastic metastases and normal tissue.
The following parameters were determined from the trabecular bone using a direct three-dimensional approach [40]: total bone marrow volume including the trabeculae (TV; mm3), trabecular bone volume (BV; mm3), trabecular bone volume fraction (BV/TV), mean trabecular number (Tb.N; 1/mm), mean trabecular thickness (Tb.Th; mm), and mean trabecular separation (Tb.Sp; mm).
Structural parameters included the apparent trabecular bone volume fraction (BV/TV), apparent trabecular number (Tb.N), apparent trabecular separation (Tb.Sp), apparent trabecular thickness (Tb.Th), mean trabecular area, mean trabecular perimeter, mean trabecular roundness and mean skeleton length [ 41].
Mean trabecular area, mean trabecular perimeter and mean skeleton length were calculated by total trabecular area, perimeter and skeleton length in ROI relative to trabecular number, respectively.
Apparent trabecular bone volume fraction (BV/TV), mean trabecular area, mean trabecular perimeter and mean skeleton length negatively correlated with Euler number in OA group.
Whole bone stiffness, trabecular bone density and trabecular plate parameters were also lower in post- versus premenopausal women.
The mean trabecular bone volume constituted 28,4 ± 3,82% with a mean trabecular width of 225,12 ± 16,30 μm.
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