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Mean total fluid bolus was 26.9 mL/kg (± 14).
Mean total fluid intake was 1604±937 ml per day.
Patients with severe sepsis were resuscitated according to clinician preference, including a mean total fluid intake over eight liters in the first 24 hours of ICU care.
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To assess the volumes of fluid administered in the treatment and control groups we calculated the difference in the mean or median total fluid volume delivered between groups.
Participants who did not complete the full fluid intake record, participants reporting a mean total daily fluid intake below 0.4 L/day or higher than 6 L/day or those who had participated in a market research study in the previous 6 months were excluded from the analysis.
Participants who did not complete the full 7 days of the fluid record, participants reporting a mean total daily fluid intake below 0.4 L/day or higher than 6 L/day or those who had participated in a market research study in the previous 6 months were excluded from the analysis.
Participants who did not complete the full 7-day fluid intake records or participants reporting a mean total daily fluid intake below 0.4 L/day or higher than 4 L/day were excluded from the analysis.
In fact the mean fluid deficit of the two procedures was limited to 750 ml with a mean of total fluid used of 9,250 ml.
Subjects reporting a mean total daily fluid intake below 0.4 L/day or higher than 6 L/day, as well as subjects not completing all 7 days of the 7-day fluid record were excluded from the analysis.
Participants who did not complete the full 7-day fluid intake record or who reported the exactly same intakes on ≥2 days over the 7 day period were excluded from the analysis, as well participants reporting a mean total daily fluid intake below 0.4 L/day or higher than 4 L/day as they are considered to be non-plausible intakes.
The contribution of each fluid type, as a proportion of the mean daily total fluid volume was also calculated.
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