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In these patients, mean total exposure prior to randomization (that is, total duration of milnacipran treatment in all prior studies and the four-week open-label period of this study) was 36.1 months (range, 17.9 to 54.4 months).
Mean total exposure values for edoxaban alone expressed as AUC0 inf ranged from mean (±SD) values of 1576.8 (±322.7) to 1965.5 (±420.9) ng·h/mL, consistent across study cohorts and with historical data [ 7, 21– 23].
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And does "show-er" mean total shower?
Wuwei does not mean total inaction.
That, to me, would mean total independence.
Average (mean) total hospital charges.
One might hypothesize that exposure from sources other than personal care products accounts for approximately half the mean total DEP exposure, with exposure from personal care products comprising the remainder.
The mean total piperaquine exposure in fasting patients was used to calculate the mean exposure in fed patients after a putative food effect, and the SD was based on that observed for fasting patients but was assumed to be proportional to exposure.
When busulphan pharmacokinetics in mice and humans were considered, the estimated systemic exposure at the therapeutically active dose in mice (113 μg h ml−1) was close to the mean total systemic exposure in children receiving high-dose busulphan (102.4 μg h ml−1).
The mean total PAH exposure was 3.7 ng/m (range, 0.4 36.5 ng/m).
In contrast, in Europe wine was reported to have contributed 10% of the mean total OTA exposure (SCOOP 2002).
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