Exact(2)
Three subjects had ostomies, and their mean stool volume decreased from 6735 ± 3764 mL/day at baseline to 4508 ± 2552 mL/day at SD84 (p = 0.2194).
Overall, the mean stool volume was 50% lower in those treated with antibiotics compared to placebo/no treatment (ROM 0.50, 95% CI 0.45 to 0.56, 17 trials, 1716 participants, Analysis 1.2).
Similar(6)
Tetracycline was also more effective than furazolidone for most outcomes examined, with these differences statistically significant for diarrhoea duration (mean difference -16.00 hours, 95% CI -31.26 to -0.74, Analysis 12.1), stool volume (Analysis 12.2), hydration requirements (Analysis 12.5), and clinical failure (Analysis 12.4).
For outcomes dependent on weight that were described in litres or mL/kg (for example, stool volume, hydration requirements), we computed the ratio of arithmetic means (ROM, Friedrich 2011; Friedrich 2012).
Major outcome measures were stool volume and frequency, ORS intake, and resolution of diarrhea.
A quantitative score based on stool volume and consistency was used for daily assessment of diarrhoea; diarrhoea was defined as a score ≥15.
41 As described, studies generally measure efficacy using stool output/48 hours, number of diarrheic stools, stool volume, and diarrhea duration.
Stool volume was periodically measured using a devise suited to collect stools separate from urine.
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