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The mean motor threshold (RMT) was 53.3% (SD 7.15) of the maximum stimulator output intensity; hence mean stimulation intensity for the experiment was 63.9% (SD 8.62).
The mean stimulation intensity necessary to induce a clinical response in these 53 electrode contacts was 9.15 (±2.2) mA and differed significantly neither between the different categories of responses (p = 0.072) nor the different patients (p = 0.797).
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Average stimulation intensity was 0.65 mA (SD 0.45).
The average stimulation intensity during rTMS was 63%.
Indeed, the mean stimulation current intensity required to evoke the first action potential is lower in dopamine depletion than in control condition (see Fig. 6B).
With a mean stimulation rate of 0.40 Hz and a mean nociceptive stimulation intensity of 1.78 × Threshold, subjects were found to systematically react with a change in PPT, either a decrease or an increase.
In the weak tACS condition we stimulated at 0.05 mA, a stimulation intensity that should not affect neural activity20.
In control animals, this fraction was initially constant as the stimulation intensity decreased, even at levels where mean firing rates had modestly diminished.
Stimulation intensity was set at 90% MT (mean 45.6 (SD 6.9)).
In all subjects, stimulation intensity was set at 70%% of the maximal stimulator output, corresponding to the mean intensity used in Exp1M1right and Exp2M1left.
Interestingly, within-cell comparison of the response magnitude at low stimulation intensities (0.06°) vs. the response at the highest stimulation intensity (1.4°) showed that, in some cases, the mean firing response was virtually identical at both stimuli intensities (Fig. 6B).
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