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Despite the drift, over shorter numbers of trials, the mean spike time of each neuron has high accuracy (Figure 9D).
It did, however, change the formation process, as neurons gradually shifted their mean spike time in response to the loss of neurons.
After recruitment into the synfire network, each neuron can spike at a precise time; the mean spike time, however, can drift forward as training proceeds.
Here, the mean spike time across 100 trials is shown as a vertical dash, and the standard deviation of the mean (jitter) as a horizontal error bar; note that it is possible to have millisecond accuracy.
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(C ) Top, jitter measured as the time of action potential occurrence relative to the mean spike timing of 3 5 trials.
FF is defined as the variance of the spike count divided by the mean spike count over some time window.
In order to remove spike remnants on the LFP channel, spikes were removed using the spike timing and the mean spike waveform.
The mean spike jitter served as a scalar measure of the overall spike timing precision in the experiment.
The removal was performed by scaling the mean spike waveform with a scaling factor computed by the inner product of the corresponding part of the LFP to the spike time and the mean spike waveform, as shown mathematically below.
We derive average models for the switching spikes and use them to construct a synthetic spike time series.
The electromyographic measures were mean spike (peak-to-peak) amplitude and mean spike frequency of the biceps and triceps brachii activity.
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