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The IDI measures the estimated improvement in the average sensitivity with the addition of adiponectin minus the estimated decrease in the mean specificity across all possible threshold values (15).
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The mean specificity score across the six goals was 5.6 (SD = 1.8) corresponding to a mean specificity rating for each goal of just under '1' on the 0 3 rating scale.
The results of this testing yielded a mean specificity of 99.7% and an accuracy of 92.2%.
Mean sensitivity was 82.12% and mean specificity was 91.88%.
Classification of non-responders in each left-out cohort was again similar to that observed with 10-fold cross validation, with a mean specificity of 94 %, a mean precision of 69%%, and a mean sensitivity of 32%% across all four data sets (Table 4).
The mean specificity of the predictors was 98%, ten of which provided a specificity of 100%.
With hardcopy films the pooled mean specificity was 89.6%.
Additionally, the mean specificity of the two models was > 65%.
Age at diagnosis was the most discriminatory feature in 7/9 studies where it was assessed, with optimal cut-offs (>70% mean sensitivity and specificity) across studies being <30 years or <40 years.
Few studies of tripartite mycoheterotrophic systems have examined ecological specificity across broad geographic ranges or addressed autotrophic host specificity.
The specificity across health worker categories was marginally lower at between 0.813 and 0.886 (Table 3).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com