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The main outcome measures are mean severity level (number of symptoms scored as positive) and health-related QoL.
The range of endoscopic severity was graphically checked by plotting the mean severity level evaluated by VAS as a function of its rank order.
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Predicted mean severity levels (and 95% CI) for different combinations of Likert scale levels of the three descriptors are shown in table 7. Relationships between actual mean overall assessments of severity (VAS) and means predicted by the model are shown in figure 4. When individual assessments were compared with predicted values, the pR was 0.78.
Overall, the degree of irritation and other respiratory symptoms during DE exposure in our study was reported as mild, with mean severity levels near the "weak" descriptor on the symptom severity scale, although some subjects reported symptoms at the "moderate" level (data not shown).
The average severity level of Lundberg et al's [ 13] sample might have been slightly lower than the average severity among our 5 health states, making the mean preference value slightly higher.
The finding that there is no significant difference between the groups for the FIS sub-dimensions that assess fatigue-related limitations in physical and cognitive functions is thought to be due to the majority of the patients in GOLD II-III stage and their mild and similar fatigue severity level (mean FSS scores <4) with controls.
Mean severity scores and antibody levels were compared using Student's t test.
This was also seen for the cognition vignettes for all sites except Kenya where the mean rating for learning vignette severity level 4 was lower than that of severity level 3 and in India where the mean ratings for both memory and learning vignette severity level 5 were lower than that for severity level 4 though these differences were not significant.
The relationship between the retinopathy severity level and mean retinal thickness (when laser-treated patients are excluded) is illustrated in Fig. 4.
Covariate adjusted mean PGWB total scores by baseline severity level are presented in Table 3.
Mean severity scores, antibody titers, and cytokine levels were compared using the Mann–Whitney test.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com