Sentence examples for mean sequencing depth from inspiring English sources

Remarkably, MALBAC has low amplification bias and can achieve 93% genome coverage ≥1× and 25× mean sequencing depth in a single cell during WGS.

MALBAC provides high uniformity in coverage across the genome (93% coverage of at least 1X at a mean sequencing depth of 25× for a single human cell) and is useful for detecting copy number variants (CNVs) in single cells; however, MALBAC has a high false positive error rate and is not appropriate for detecting point mutations [8].

Using specifically developed statistical methods that account for DNA pooling, low mean sequencing depth, and sequencing errors, we provide genome-wide estimates of nucleotide diversity and genetic differentiation in pig.

The mean sequencing depth was 8 to 10 times.

Mean sequencing depth per base for phase 1 samples was 1,999, rising to 4,035 for phase 2 samples.

Costs can be lowered by reducing the mean sequencing depth, but this results in genotype calls of lower quality.

We "sequenced" each allele to a depth determined by a draw from a Poisson distribution at three different mean sequencing depths (10×, 20×, and 40×).

Coverage mapping of the merged assemblies for Sulcia-ALF and the Nasuia-ALF produced unbroken scaffolds with high mean sequencing depths of 500× and 850×, respectively.

The mean sequence depth was 874 1,457× per base.

The first two moments of our simulated data were examined, resulting in a mean sequence depth of around 1950 reads per pool and variance of 12 026.

First, we simulated Escherichia coli read data with mean sequence depth from 5 × to 100 × to investigate the computational complexity of the overlap algorithms as a function of depth.