Sentence examples for mean sequence similarity from inspiring English sources
The mean sequence similarity between a zebra finch EST and its matching chicken orthologue was 91.6%.
Surprisingly, both mean sequence similarity and the density of motifs localization were increased towards 3'-end of these RNAs.
We test them on the global unconstrained alignment of the fly and yeast networks, and show that for a given level of mean sequence similarity between matched proteins, our new method retrieves 78% more conserved interactions than IsoRank.
λ=1 corresponds to the maximization of J PP ) only, i.e. to find a good topological matching of the graphs independently of the similarity between matched pairs, while λ=0 amounts to focus only on the similarity between proteins and finding a matching which maximized the mean sequence similarity, without using PPI information.
In the proposed method, chemical space means the chemical structure similarity space of possible chemical compounds, genomic space means the amino acid sequence similarity space of possible proteins and pharmacological space means the interaction space reflecting the drug target interaction network, where interacting drugs and target proteins are close to each other.
Combining the results of the K means analysis with the sequence similarity analysis; we speculated that these four transcripts should be putative monoterpenol glucosyltransferases.
The relatively high rate of recombination in V. cholerae means that the level of sequence similarity does not indicate relatedness of the isolates unless the sequences are very similar and differences can be attributed to mutation, as in the toxigenic strains.
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To test the prediction that TFs with similar sequences should tend to have similar function, we examined TFs in E. coli, yeast and human, and compared their sequence similarity by means of several distance metrics.
Further, sequence similarity does not always mean functional similarity and this may influence the interpretation of our results as minor sequence dissimilarities may represent functional different or even a completely new functions.
But sequence similarity does not strictly mean functional similarity.
