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Based on mean sequence identity and standard deviation, we calculated Z-scores for data sets of antibody sequences extracted from the Kabat database.
DNA sequence similarity for conserved regions was calculated as the mean sequence identity of the homologous regions, weighted by each region's length in nucleotides.
The mean sequence identity is 24%.
The mean sequence identity of these homeologous copies was 98.66%, while the minimum was 95.05%.
G. lamblia kinase domains were also found to have a mean sequence identity of only 40% with H. sapiens, lower than plant and fungal kinases 49-500%).
Pairwise alignment of all DMA1 and DMA2 monomer units revealed significant sequence homology in the first 100 bp of both repeats (80.2% mean sequence identity), suggesting that the two satellite families have a common evolutionary history.
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Blue shading means 100% sequence identity, pink shading means more than 75% sequence identity, light blue means more than 50% sequence identity; underline means specific domain of thiolase.
The second metric aims at removing divergent groups, defined as groups with mean protein sequence identity (mean of pairwise identity values when comparing all sequences within group) smaller than user-defined cutoff.
2 families had no sampled alignments with a mean pairwise sequence identity larger than 60%.
A mean transcript sequence identity of 97% was found between ovine and bovine orthologs, which probably highlights the utility of the microarray technique with ovine samples [ 25].
The two groups share a mean nucleotide sequence identity of slightly less than 75% and a CP amino acid sequence identity of ≤85%, with a much lower mean percentage identity (ca. 74%) for all of the proteins.
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mean percentage identity
mean percent identity
mean sequence distance
mean sequence coverage
mean sequence divergence
mean sequence length
mean sequence gap
mean sequence quality
mean group identity
mean maximum identity
mean pairwise identity
mean intragroup identity
mean sequence depth
mean gender identity
mean hydrophobicity identity
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