Exact(3)
The main outcome measure was post-index mean sUA levels.
16 35 The reasons for this increased risk remain unclear, but prolonged exposure to hyperuricaemia prior to the onset of clinical gout may play a role, since women have been observed to have an older mean age at onset of gout, lower mean SUA levels, and reduced risk of incident gout compared with men with a comparable level of hyperuricaemia.
It has been suggested that the potential renoprotective effect observed in one study of allopurinol may have been caused by lowering SUA levels from slightly above to slightly below the uric acid saturation point (6.8 mg/dL); mean SUA levels over the 7-year observation period were 7.2 mg/dL in the control group and 6.5 mg/dL in the allopurinol-treated group.
Similar(57)
The mean SUA level of patients having type 2 diabetes was significantly lower than that of control subjects (6.1 ± 1.8 mg/dL v 6.6 ± 1.8 mg/dL, P <.001); and the mean SUA level of diabetic patients with ecNOS ab/aa genotypes was lower than that of patients with bb genotype (5.7 ± 1.6 mg/dL v 6.2 ± 1.8 mg/dL, P =.008).
In patients with coronary artery disease, the mean SUA level in valsartan users was increased compared with the baseline [ 27].
The mean SUA level in each age group in 2001 was higher than that of in 1996(see Table 1).
In losartan users, mean SUA level was significantly decreased from baseline, while it was conversely increased in users of other ARBs; valsartan, telmisartan, candesartan, and olmesartan.
When the mean SUA level was not reported, the range's midpoint in each category was used, except for the lowest and highest category, for which the mean SUA level was estimated by assuming normality of SUA distribution, which is the same method as used in a previously published meta-analysis (8).
Mean SUA level of subjects ranged from 4.0 to 8.0 mg/dl, and mean age ranged from 41 to 63 years except for one study (23), in which data on mean age (>55 years) were not available.
We identified country of origin (Asian or Western countries), mean age (>50 or ≤50 years), sex (whether men only, women only, or both men and women), and mean SUA level (>5.5 or ≤5.5 mg/dl) as possible participant characteristics.
The mean sUA level was 4.69 ± 1.08 mg/dL in normouricemic Group A and 7.61 ± 0.95 mg/dL in Group B (p < 0.001), indicating a difference of 2.9 mg/dL.
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