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Exact(5)
The sixth mRNA construct, for DVL2, showed > 40% mean reduction with small variance at 10 nM (p<0.467), but an increased expression at 50 nM (Figure 8B).
Thus, the mean reduction with treatment was 3.3 cm (paired t-test: P < 0.0001, Table 1).
For all doses combined, the mean initial concentration of LDL cholesterol was 4.5 mmol/L and mean reduction with pravastatin was 1.2 mmol/L (27%).
For all doses combined, the mean initial concentration of total cholesterol was 6.6 mmol/L and mean reduction with pravastatin was 1.3 mmol/L (20%).
For all doses combined the mean initial concentration of triglycerides was 1.8 mmol/L and mean reduction with pravastatin was 0.2 mmol/L (12%).
Similar(55)
Indeed, there is evidence that decreases in blood pressure are greater in patients with hypertension (baseline blood pressure ≥140/90 mmHg), with a mean reduction of 13.1/6.3 with rimonabant 20 mg/day compared with 7.2/2.4 mmHg with placebo (Després et al. 2005a).
We calculated that 40 participants per group would be required for the study to have 80% power to show a clinically significant 25% mean reduction in pain with distant reiki as compared with placebo.
As expected, the group of patients diagnosed with post-herpetic neuralgia had a mean reduction of pain with respect to baseline similar to that reported in the registration clinical trials [ 13].
Total cortical area (TCA) was reduced by low P treatment for all genotypes (mean reduction 16.8 %), with Pokkali exhibiting the greatest reduction (28%%) and Aichi Asahi the least (2.6 %), which was similar to the effects of low P on RXSA (Fig. 6).
The mean reduction in HbA1c with vildagliptin was typically up to 1 percentage point (Table 3).
A mean reduction by 0.56 with a minimum difference of 0.22 considered as clinically important [ 21] showed that functional ability was meaningfully improved under treatment.
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