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This results in a mean red marrow over blood ratio of 0.88 (value not significantly different from 1).
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The mean absorbed dose of Y-rituximab to the red marrow was threefold higher.
The maximum uptake by red marrow was about 2% of the injected activity, and the mean absorbed dose per administered activity was 2.26E-2 2.26E-2-3 mGy/MBq.
She does a mean red.
S RM←RM corresponds to the 'red marrow to red marrow' contribution, and S RM←RB corresponds to the 'remainder of the body to red marrow' contribution.
Noteworthy, the canine study differentiated between yellow and red marrow, finding markedly less perfusion in yellow than in red marrow.
mDOTA = 90Y-DOTATOC red marrow dose per megabecquerel.
The residence time of all red marrow in the body was estimated from the lumbar vertebrae, which contains both red marrow and bone.
The stomach, red marrow, urinary bladder and lungs had long residence times.
Applying this assumption, the red marrow absorbed dose per unit-administered activity is 29 mGy/kBq.
The residence times for the spleen and red marrow were calculated from the blood residence time.
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